Table 2. Protein identifications in A. suum L3-lung ES products.
| Category/Protein identitya | IDb | Score | Coverage | Unique sequences | emPAI | Sigc |
| % | ||||||
| Metabolic pathway | ||||||
| Maltase-glucoamylase | GS_07553 | 78 | 2 | 1 | 0.05 | + |
| GS_15893 | 142 | 6 | 2 | 0.15 | − | |
| GS_16769 | 132 | 8 | 3 | 0.18 | ++ | |
| GS_23879 | 171 | 4 | 4 | 0.08 | ++ | |
| Neprilysin-1 | GS_08219 | 66 | 1 | 1 | 0.02 | + |
| Sucrase-isomaltase | GS_01568 | 277 | 19 | 4 | 0.66 | − |
| GS_02444 | 258 | 13 | 3 | 0.28 | − | |
| GS_05716 | 80 | 11 | 1 | 0.19 | − | |
| GS_08447 | 69 | 2 | 1 | 0.04 | ++ | |
| GS_17323 | 129 | 3 | 1 | 0.05 | − | |
| GS_20796 | 121 | 2 | 1 | 0.04 | − | |
| GS_22047 | 151 | 6 | 3 | 0.12 | ++ | |
| Structural | ||||||
| Cuticlin-1 | GS_10816 | 63 | 3 | 1 | 0.09 | − |
| Cuticle collagen 12 | GS_16238 | 147 | 17 | 2 | 0.27 | ++ |
| Cuticle collagen 13 | GS_12737 | 289 | 8 | 1 | 0.34 | ++ |
| Peptidyl-prolyl cis-trans isomerase B | GS_15602 | 197 | 7 | 2 | 0.29 | − |
| Binding | ||||||
| 14-3-3-like protein | GS_05590 | 73 | 3 | 1 | 0.11 | − |
| C-type lectin | GS_12842 | 102 | 49 | 2 | 1.70 | − |
| Latent-transforming growth factor beta-binding protein 1 | GS_21305 | 102 | 0 | 1 | 0.01 | ++ |
| Thyrotropin-releasing hormone-degrading ectoenzyme | GS_02555 | 123 | 4 | 1 | 0.08 | ++ |
| Transmembrane cell adhesion receptor mua-3 | GS_11192 | 253 | 2 | 6 | 0.06 | ++ |
| Other | ||||||
| Aspartic protease 6 | GS_13572 | 239 | 9 | 2 | 0.25 | + |
| Pepsin inhibitor Dit33 | GS_22518 | 81 | 6 | 1 | 0.13 | ++ |
| Poly(U)-specific endoribonuclease | GS_22743 | 101 | 4 | 1 | 0.05 | + |
| Protein DAO-2 | GS_24324 | 120 | 13 | 1 | 0.54 | + |
| Serine protease | GS_07735 | 78 | 2 | 1 | 0.05 | + |
| Serpin-like protein | GS_19115 | 303 | 14 | 2 | 0.29 | − |
| Unknown | ||||||
| 24 kDa protein of As22 | GS_08591 | 219 | 17 | 2 | 0.36 | + |
| DOMON domain-containing protein | GS_00339 | 144 | 20 | 2 | 0.43 | − |
| Excretory/secretory mucin MUC-5 | GS_22776 | 529 | 56 | 1 | 4.62 | ++ |
| Heh-1 | GS_20415 | 66 | 5 | 1 | 0.12 | − |
| Transthyretin-like protein 5 | GS_01881 | 85 | 9 | 1 | 0.25 | + |
| Venom allergen 3 | GS_10381 | 103 | 12 | 2 | 0.26 | ++ |
| von Willebrand factor domain-containing protein | GS_02090 | 66 | 3 | 1 | 0.07 | ++ |
| Hypothetical protein LOAG_00319 | GS_14306 | 72 | 14 | 1 | 0.30 | − |
| Hypothetical protein LOAG_07538 | GS_11367 | 109 | 5 | 1 | 0.12 | − |
| Unknown | GS_01811 | 72 | 14 | 1 | 0.29 | − |
| Unknown | GS_02698 | 83 | 11 | 1 | 0.33 | − |
| Unknown | GS_03310 | 89 | 4 | 1 | 0.14 | + |
| Unknown | GS_09456 | 119 | 20 | 2 | 0.56 | + |
| Unknown | GS_10718 | 171 | 34 | 2 | 0.92 | + |
| Unknown | GS_12589 | 133 | 11 | 1 | 0.58 | + |
| Unknown | GS_15853 | 245 | 18 | 2 | 0.67 | − |
| Unknown | GS_17230 | 198 | 11 | 2 | 0.49 | − |
| Unknown | L3E_00366 | 150 | 4 | 1 | 0.21 | − |
a
The proteins identified were categorized by their molecular function according to information obtained from the Gene Ontology database.
b
The accession number in A. suum genome database (available on WormBase, www.wormbase.org).
c
The identified proteins were predicted to be either a classical secretory protein (+), non-classical secretory protein (++) or not secreted (−) by secretion prediction using SignalP and SecretomeP.