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. 2013 Oct 3;9(10):e1003756. doi: 10.1371/journal.pgen.1003756

Table 1. The forespore line of expression with the identification of the σF and σG regulon.

Gene Name Function Expression ratio in transcriptomea Promoterb Detection in spore c operon
Members of the σF regulon sigF/630Δerm
sporulation
CD0125 spoIIQ Stage II sporulation protein Q 0.11 σF −
CD2470 gpr Spore endopeptidase 0.22 σF + CD2470-CD2468
CD2469 spoIIP Stage II sporulation protein P 0.14 −
CD2468 Conserved hypothetical protein 0.28 −
CD3564 spoIIR Pro-SigE endopeptidase signalling protein 0.43 σF − CD3564-CD3563
CD3563 sleB Spore-cortex-lytic protein 0.16 −
CD0783 spoIVB' SpoIVB protein, S55 peptidase family 0.10 −
envelopes
CD2141 Serine-type D-Ala-D-Ala carboxypeptidase 0.30 −
CD1229 Putative peptidoglycan glycosyltransferase 0.42 σF −
CD2686 Putative membrane protein 0.33 σF −
CD2856 Putative membrane protein 0.46 σF −
CD2107 Xanthine/uracil/thiamine permease family 0.37 −
CD2102 Putative Na(+)/H(+) antiporter 0.49 σA −
miscellaneous
CD0580 gapN Glyceraldehyde-3-phosphate dehydrogenase 0.36 σF +
CD3595 Aminopeptidase 0.55 σF +
CD2661 Putative peptidase, M16 family 0.47 + CD2661-CD2660
CD2660 Putative peptidase, M16 family 0.48 +
CD0047 ispD 2-C-methyl-D-erythritol 4-P cytidylyltransferase 0.48 σA − CD0047-CD0048
CD0048 ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 0.50 −
CD3220 Putative methyltransferase 0.39 σA −
CD0761 Putative ATP-dependent RNA helicase 0.46 σF and σA +
CD1323 tepA Protein export-enhancing factor 0.38 +
proteins of unknown function
CD0347 Conserved hypothetical protein 0.35 σF − CD0347-CD0348
CD0348 Fragment of conserved hypothetical protein 0.35 −
CD2687 Conserved hypothetical protein 0.36 −
a

A gene is considered differentially expressed when the P value is <0.05 using the statistical analysis described in Materials and Methods.

b

We search for promoters recognized by the different sigma factors active in forespore upstream of the TSS mapped by RNA-seq. These promoters are listed in Table S6. 3 promoters with the −10 and/or −35 elements less conserved are indicated with a question mark.

c

Proteins that are detected associated with the spore by a proteomic approach [39].