Figure 6. Genetic context of the hyxA and hyxR genes and their role in O-antigen synthesis.
(A) The conserved location of PAI-X containing hyxAR genes in E. coli genomes of various pathotypes. (B) The LPS pattern of the hyxA and hyxR mutants and their complemented strains, demonstrating a role for the hyxA and hyxR genes in O-antigen chain length regulation. Red boxes highlight differences in LPS patterns compared with that of the wild-type.