. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Am J Psychiatry. 2013 Oct 1;170(10):1152–1160. doi: 10.1176/appi.ajp.2013.12101294

Table 2.

Total brain and regional brain gray matter and white matter volumes

Anatomical Region		Control Women (A)		Anorexia Nervosa Women (B)		Recovered-Anorexia Nervosa Women (C)		Bulimia Nervosa Women (D)
		Mean	SD	Mean	SD	Mean	SD	Mean	SD	F	p
Whole Brain Volumes
GM Volume (cm³)		629.7	62.1	651.8	37.9	639.4	49.5	662.4	40.6	1.8	0.149
WM Volume (cm³)		494.0	44.3	503.8	41.0	493.0	56.3	503.3	68.2	0.3	0.856
CSF Volume (cm³)		226.8	30.6	246.3	33.1	226.5	26.6	233.2	28.0	2.0	0.118
Total Intracranial Volume (cm³)		1350.5	105.3	1402.0	71.6	1358.8	107.0	1398.9	117.8	1.5	0.232

Regional GM Volumes	MNI Coordinates
L Orbitofrontal Cortex	x=-6, y=29, z=-26	0.479	0.071	0.553	0.091	0.538	0.066	0.585	0.072	7.9	<0.001	B>A^, D>A^*, C>A^
R Anterior Ventral Insula	x=30, y=14, z=-12	0.704	0.079	0.806	0.084	0.754	0.084	0.777	0.104	5.3	0.002	B>A^***
R Anterior, Middle Insula	x=42, y= 9, z= 4	0.597	0.058	0.679	0.066	0.645	0.063	0.630	0.069	6.1	0.001	B>A^**, C>A^
L Anterior Ventral Insula	x=-29, y=12, z=-17	0.703	0.059	0.753	0.077	0.729	0.066	0.769	0.070	4.0	0.011	D>A^**
R Dorsal Caudate	x=21, y=-3, z=19	0.173	0.019	0.170	0.017	0.153	0.018	0.147	0.021	10.2	<0.001	A>D^*, A>C^, B>D^*, B>C^
L Dorsal Caudate	x=-20, y=-3, z=18	0.308	0.027	0.295	0.032	0.281	0.034	0.270	0.036	5.7	0.001	A>D^*, A>C^
R Dorsal Putamen	x=20, y=0, z=12	0.173	0.013	0.168	0.016	0.157	0.017	0.151	0.015	9.2	<0.001	A>D^*, A>C^, B>D^*
R Dorsal Putamen	x=23, y=0, z=15	0.088	0.008	0.086	0.009	0.080	0.009	0.076	0.008	9.1	<0.001	A>D^*, A>C^, B>D^**

Regional WM Volumes	MNI Coordinates
R Medial Temporal Lobe	x=27, y=-19, z=-5	0.770	0.057	0.754	0.052	0.727	0.056	0.713	0.044	5.3	0.002	A>D^**
R Inferior Temporal Lobe	x=57, y=-20, z=-21	0.594	0.047	0.585	0.046	0.565	0.044	0.546	0.034	9.3	<0.001	A>B^, A>C^, D>B^, D>C^*
R Inferior Parietal Lobe	x=55, y=-48, z=35	0.347	0.065	0.353	0.081	0.278	0.056	0.285	0.056	8.0	<0.001	A>D^, A>C^, B>D^, B>C^*

Manually Traced Orbitofrontal Gyrus Rectus Volume, mm³		868	247	1128	438	1205	384	1282	449	5.1	0.003	A<B^, C^, D^**

Dunnett T3 post hoc test

p<0.05

^**

p<0.01

^***

p<0.001.

Values for regional brain volumes are fractions of the respective brain tissue type per volume.