Table 1.
Presenting the characteristics of patients with and without albuminuria
| Pairs with direct relationship | Pairs with reverse relationship | ||||
|---|---|---|---|---|---|
| With albuminuria (n = 30) | Without albuminuria (n = 30) | With albuminuria (n = 10) | Without albuminuria (n = 10) | ||
| Age (years) | 57 ± 2.1 | 58 ± 2.4 | 55 ± 3.6 | 58 ± 2.5 | |
| Female (n, %) | 14 | 14 | 5 | 5 | |
| Family history diabetes (n) | 14 | 20 | 8 | 7 | |
| Statins | 7 | 16 | 5 | 5 | |
| Drug diabetes | Glibenclamide | 5 | 2 | 3 | 1 |
| Glibenclamide + metformin | 1 | 6 | 3 | 1 | |
| Metformin + insulin | 15 | 11 | 2 | 6 | |
| Insulin | 1 | 6 | 2 | 1 | |
| Metformin | 8 | 5 | 0 | 1 | |
| Smoking (n) | 1 | 1 | 0 | 2 | |
| Diabetes duration (years) | 11 ± 1.6 | 9 ± 1.1 | 4 ± 2.0 | 9 ± 2.1 | |
| BMI (kg/m2) | 26 ± 0.7 | 26 ± 0.8 | 27 ± 1.6 | 26 ± 1.1 | |
| Waist circumference (cm) | 93 ± 1.8 | 92 ± 2.0 | 93 ± 2.8 | 92 ± 2.0 | |
| Systolic blood pressure (mmHg) | 123 ± 3.6 | 126 ± 4.5 | 122 ± 5.0 | 112 ± 5.6 | |
| Diastolic blood pressure (mmHg) | 72 ± 1.7 | 73 ± 2.3 | 70 ± 2.3 | 70 ± 2.6 | |
| HbA1c (%) | 9.3 ± 0.4 | 8.6 ± 0.4 | 6.5 ± 0.4 | 8.0 ± 0.7 | |
| Fasting blood sugar (mg/dl) | 217 ± 16.4 | 184 ± 12.6 | 133 ± 11.1 | 182 ± 39.2 | |
| HSP 70 (ng/ml) | 0.93 ± 0.05* | 0.51 ± 0.02 | 0.57 ± 0.03** | 0.96 ± 0.19 | |
| HDL (mg/dl) | 39 ± 1.1 | 41 ± 2.0 | 41 ± 2.6 | 42 ± 3.6 | |
| LDL (mg/dl) | 103 ± 5.8 | 103 ± 8.5 | 88 ± 9.1*** | 122 ± 9.3 | |
| Triglyceride (mg/dl) | 199 ± 25.9 | 169 ± 23.6 | 150 ± 18.1 | 139 ± 17.9 | |
| Cholesterol (mg/dl) | 191 ± 9.1 | 174 ± 9.7 | 168 ± 10.6 | 202 ± 14.7 | |
| eGFR (ml/min) | 65 ± 3.5 | 67 ± 5.0 | 70 ± 3.1 | 75 ± 10 | |
When comparing patients with and without albuminuria, pairs with direct relationship are the pairs which HSP70 is higher in cases, and pairs with reverse relationship are the pairs which HSP70 is higher in controls
*p < 0.001; **p < 0.05; ***p < 0.01