Table 2.
Hematology and serum biochemistry parameters in the study population at baseline and 3-month visits
| Baseline visit | 3-month visit | P value | |||
|---|---|---|---|---|---|
| Valid N a | Mean (SD) | Valid N a | Mean (SD) | ||
| Hemoglobin (g/dL) | 667 | 10.1 (0.8) | 527 | 11.2 (1.5) | <0.001 |
| Hematocrit (%) | 650 | 30.5 (2.7) | 519 | 33.6 (4.5) | <0.001 |
| Leucocyte (103/mm3) | 654 | 6.3 (3.6) | 522 | 6.3 (3.4) | 0.666 |
| Lymphocytes (103/mm3) | 386 | 1.4 (0.7) | 280 | 1.4 (0.7) | 0.706 |
| Neutrophils (103/mm3) | 389 | 3.9 (2.5) | 278 | 3.8 (2.1) | 0.716 |
| Platelets (103/mm3) | 637 | 282.2 (133.2) | 519 | 247.7 (111) | <0.001 |
| Sodium (mEq/L) | 474 | 139.2 (3.2) | 414 | 139.5 (3.4) | 0.133 |
| Potassium (mEq/L) | 466 | 4.3 (0.5) | 403 | 4.3 (0.5) | 0.326 |
| AST (U/L) | 395 | 25.9 (23.8) | 348 | 32.5 (31.8) | 0.002 |
| ALT (U/L) | 408 | 28.2 (22.9) | 356 | 29.5 (22.7) | 0.243 |
| Glucose (mmol/L) | 486 | 5.9 (1.9) | 421 | 5.7 (1.7) | 0.007 |
| Albumin (g/dL) | 254 | 3.8 (0.6) | 250 | 3.9 (0.6) | <0.001 |
| Bilirubin (mg/dL) | 410 | 0.5 (0.4) | 357 | 0.6 (0.3) | 0.164 |
| Creatinine (mg/dL) | 550 | 0.9 (0.4) | 470 | 0.9 (0.4) | 0.380 |
| LDH (U/L) | 300 | 424.8 (242.9) | 276 | 404.3 (222) | 0.329 |
| Serum iron (μg/dL) | 78 | 51.2 (33.5) | 71 | 58.9 (28.5) | 0.026 |
| Ferritin (ng/dL) | 48 | 300.3 (316.4) | 49 | 275.8 (291.2) | 0.652 |
| Transferrin (%) | 37 | 18 (7.5) | 41 | 17.8 (8.8) | 0.837 |
| Vitamin B12 (pg/mL) | 40 | 582.9 (501.4) | 45 | 592.1 (400.1) | 0.400 |
| Folic acid (ng/mL) | 39 | 9.2 (6) | 34 | 10.3 (6.2) | 0.518 |
| Endogenous EPO (IU/L) | 4 | 56.7 (39.9) | 7 | 50.8 (30.5) | 0.777 |
ALT alanine aminotransferase, AST aspartate aminotransferase, EPO epoetin, LDH lactate-dehydrogenase
aThere were missing values in the data set