Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Properties of wild-type (WT) human ISCU and single-site amino acid variants at pH 8 and 25 °C
| Structural property | WT | D39V | N90A | D39A | H105A |
|---|---|---|---|---|---|
| %S (determined by NMR) = ([S]/([S] + [D])) × 100 (%) | 27.5 | 100 | 95.4 | 29.1 | 11.2 |
| Molar ellipticity at 220 nm (104 deg cm2 dmol−1) | 0.742 | 0.926 | 1.01 | 0.568 | 0.476 |
| Predicted α-helix (%) | 16.2 | 25.5 | 25.0 | ||
| Predicted β-strand (%) | 18.2 | 19.2 | 20.2 |
