FIGURE 3.

Phylogenetic tree analysis of plant and bacterial type III PKSs. Multiple sequence alignment, performed with ClustalW (1.8). The scale represents 0.1 amino acid substitutions per site. Abbreviations used are as follows: ALS, aloesone synthase; BBS, bibenzyl synthase; BIS, biphenyl synthase; BPS, benzophenone synthase; CTAS, 4-coumaroyltriacetic acid synthase; CUS, curcuminoid synthase; CURS, curcumin synthase; DCS, diketide-CoA synthase; HKS, hexaketide synthase; OKS, octaketide synthase; ORAS, 3′-oxoresorcinolic acid synthase; PCS, pentaketide chromone synthase; 2PS, 2-pyrone synthase; STS, stilbene synthase; THNS, tetrahydroxynaphthalene synthase; VPS, valerophenone synthase. The β-ketoacyl carrier protein synthase III (KAS III and FABH) enzymes of E. coli were employed as out groups.