Comparison of the active site structures of C. microcarpa QNS and ACS and other type III PKSs, and their schematic representations.
A, C. microcarpa QNS; B, C. microcarpa ACS; C, M. sativa CHS, and D, R. palmatum BAS. The naringenin in M. sativa CHS and the bound monoketide intermediate in R. palmatum BAS are shown as magenta and pink stick models, respectively. Arrows indicate the substrate entrance in each structure.