A, histological studies of NTG, α-Tm E180G, and DMTG hearts at 3 months of age stained with H&E, Masson's trichrome, and wheat germ agglutinin (WGA). Images were taken at 40×, and scale bars indicate 50 μm. B, cardiomyocyte cross-sectional area measurements (n = 6). *, versus NTG, p < 0.05; #, versus α-Tm E180G, p < 0.05. C, heart weight to body weight (HW:BW) ratios of 3-month-old mice (n = 6). Error bars represent S.E.