TABLE 1.
Review of published experimental conditions in which mitochondrial protein hyperacetylation is observed
Experimental condition | Tissue showing mitochondrial protein hyperacetylation | Reported time to mitochondrial protein hyperacetylation after onset of experimental condition | Reference |
---|---|---|---|
Fasting | Liver | 12–48 h | 34 |
Caloric restriction | Liver | 16–18 weeks, possibly earlier | 36 |
Chronic alcohol consumption | Liver | 3–6 weeks | 35 |
High fat diet | Liver | 13 weeks, possibly earlier | 9 |
SIRT3 KO | Liver, brown adipose, skeletal muscle | 12–13 weeks, possibly earlier | 8, 9, 28 |
Frataxin conditional KO | Heart | 3.5 weeks, NSE-Cre | 7 |
Hint2 KO | Liver | 20 weeks, possibly earlier | 11 |