Table 3. Recent alcohol consumption and breast cancer risk among AA women in WCHS.
|
|
|
OR1 |
OR2 |
||
---|---|---|---|---|---|---|
Cases (n) | Controls (n) | Estimate | 95% CI | Estimate | 95% CI | |
Total ethanol from recent alcohol intake | ||||||
Non-drinker | 503 | 531 | Ref | Ref | ||
Drinker | 300 | 357 | 0.98 | 0.79–1.20 | 0.95 | 0.77–1.17 |
<14 g per week | 131 | 153 | Ref | Ref | ||
14−<28 g per week | 60 | 70 | 1.00 | 0.64–1.56 | 0.98 | 0.63–1.53 |
⩾28 g per week | 109 | 134 | 1.01 | 0.70–1.46 | 0.95 | 0.65–1.39 |
P for linear trend |
|
|
0.97 |
0.80 |
||
Ethanol from recent beer intake | ||||||
Non-beer drinker | 684 | 725 | Ref | Ref | ||
Beer drinker | 117 | 163 | 0.84 | 0.64–1.10 | 0.81 | 0.62–1.06 |
<14 g per week | 69 | 92 | Ref | Ref | ||
14−<28 g per week | 22 | 21 | 1.65 | 0.78–3.51 | 1.67 | 0.79–3.57 |
⩾28 g per week | 26 | 50 | 0.77 | 0.41–1.45 | 0.79 | 0.41–1.49 |
P for linear trend |
|
|
0.30 |
0.31 |
||
Ethanol from recent wine intake | ||||||
Non-wine drinker | 587 | 637 | Ref | Ref | ||
Wine drinker | 216 | 251 | 0.98 | 0.78–1.23 | 0.94 | 0.75–1.19 |
<14 g per week | 109 | 126 | Ref | Ref | ||
14−<28 g per week | 50 | 69 | 0.87 | 0.54–1.40 | 0.85 | 0.53–1.38 |
⩾28 g per week | 57 | 56 | 1.16 | 0.71–1.88 | 1.10 | 0.67–1.80 |
P for linear trend |
|
|
0.45 |
0.58 |
||
Ethanol from recent liquor/mixed drinks intake | ||||||
Non-liquor drinker | 637 | 691 | Ref | Ref | ||
Liquor drinker | 166 | 197 | 1.08 | 0.84–1.38 | 1.06 | 0.83–1.36 |
<14 g per week | 109 | 146 | Ref | Ref | ||
14−<28 g per week | 21 | 19 | 1.54 | 0.75–3.16 | 1.50 | 0.73–3.08 |
⩾28 g per week | 36 | 32 | 1.57 | 0.88–2.81 | 1.53 | 0.84–2.79 |
P for linear trend | 0.13 | 0.16 |
Abbreviations: AA= African-American; BMI=body mass index; CI=confidence interval; HRT= hormone replacement therapy; OC=oral contraceptive; OR=odds ratio; WCHS=Women's Circle of Health Study.
OR1: adjusted for age, ethnicity, country of origin, education, age at menarche, parity, age at first birth, breastfeeding status, menopausal status, family history of breast cancer, HRT use, OC use, history of benign breast disease.
OR2: further adjusted for total energy intake and BMI.
Recent alcohol consumption is measured as alcohol consumption during the 12 months before reference date for cases and controls.