Table 4. Association between lifetime alcohol consumption, drinking at different age intervals, and breast cancer risk among AA women in WCHS.
| |
|
|
OR1 |
OR2 |
||
|---|---|---|---|---|---|---|
| Cases (n) | Controls (n) | Estimate | 95% CI | Estimate | 95% CI | |
|
Lifetime alcohol intake | ||||||
| Never | 537 | 568 | Ref | Ref | ||
| Ever | 266 | 320 | 0.99 | 0.80–1.23 | 0.96 | 0.78–1.19 |
| Non-drinkera | 537 | 568 | Ref | Ref | ||
| ⩽3510 drinks | 150 | 158 | 1.14 | 0.87–1.48 | 1.11 | 0.85–1.45 |
| >3510 drinks |
107 |
156 |
0.81 |
0.61–1.08 |
0.77 |
0.58–1.03 |
|
Drinking during <20 years | ||||||
| No | 728 | 760 | Ref | Ref | ||
| Yes |
75 |
127 |
0.68 |
0.50–0.94 |
0.65 |
0.47–0.89 |
|
Drinking during 20–29 years | ||||||
| No | 597 | 634 | Ref | Ref | ||
| Yes |
206 |
254 |
0.98 |
0.78–1.23 |
0.94 |
0.75–1.19 |
|
Drinking during 30–39 years | ||||||
| No | 595 | 627 | Ref | Ref | ||
| Yes |
197 |
245 |
0.94 |
0.74–1.18 |
0.91 |
0.72–1.15 |
|
Drinking during 40–49 years | ||||||
| No | 559 | 582 | Ref | Ref | ||
| Yes |
141 |
159 |
1.02 |
0.78–1.33 |
0.99 |
0.76–1.30 |
|
Drinking during 50–59 years | ||||||
| No | 390 | 388 | Ref | Ref | ||
| Yes |
72 |
79 |
1.02 |
0.70–1.47 |
1.00 |
0.69–1.45 |
|
Drinking during ⩾60 years | ||||||
| No | 162 | 130 | Ref | Ref | ||
| Yes | 10 | 17 | 0.44 | 0.18–1.06 | 0.42 | 0.17–1.01 |
Abbreviations: AA= African-American; BMI=body mass index; CI=confidence interval; HRT= hormone replacement therapy; OC=oral contraceptive; OR=odds ratio; WCHS=Women's Circle of Health Study.
OR1: adjusted for age, ethnicity, country of origin, education, age at menarche, parity, age at first birth, breastfeeding status, menopausal status, family history of breast cancer, HRT use, OC use, history of benign breast disease.
OR2: further adjusted for total energy intake and BMI.
Fifteen women had missing data for number of drinks consumed.