Table 5. Recent and lifetime alcohol consumption stratified by menopausal status and hormone receptor status in AA women.
| |
Premenopausal (n=871) |
Postmenopausal (n=821) |
ER+/PR+ |
ER−/PR− |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ca/Co | OR | 95% CI | Ca/Co | OR | 95% CI | Ca | OR | 95% CI | Ca | OR | 95% CI | |
|
Recent alcohol intake | ||||||||||||
| Non-drinker | 225/267 | Ref | 278/264 | Ref | 202 | Ref | 114 | Ref | ||||
| Drinker | 183/195 | 1.21 | 0.90–1.62 | 117/162 | 0.78 | 0.57–1.07 | 121 | 0.93 | 0.70–1.23 | 61 | 0.89 | 0.62–1.27 |
| <14 g per week | 81/87 | Ref | 50/66 | Ref | 53 | Ref | 22 | Ref | ||||
| 14–<28 g per week | 32/41 | 0.81 | 0.45–1.48 | 28/29 | 1.14 | 0.55–2.36 | 26 | 1.01 | 0.57–1.81 | 13 | 1.25 | 0.57–2.77 |
| ⩾28 g per week | 70/67 | 1.18 | 0.71–1.95 | 39/67 | 0.73 | 0.39–1.35 | 42 | 0.86 | 0.52–1.44 | 26 | 1.20 | 0.61–2.39 |
|
P for linear trend |
|
0.38 |
|
0.23 |
|
0.53 |
|
0.69 |
||||
|
Lifetime alcohol intake | ||||||||||||
| Never | 285/304 | Ref | 252/264 | Ref | 213 | Ref | 109 | Ref | ||||
| Ever | 123/159 | 0.90 | 0.66–1.24 | 143/161 | 1.07 | 0.79–1.46 | 110 | 0.98 | 0.74–1.31 | 66 | 1.14 | 0.80–1.63 |
| Non-drinker | 285/304 | Ref | 252/264 | Ref | 213 | Ref | 109 | Ref | ||||
| ⩽3510 drinks | 77/92 | 1.00 | 0.69–1.46 | 73/66 | 1.33 | 0.89–2.00 | 68 | 1.23 | 0.87–1.74 | 35 | 1.21 | 0.78–1.89 |
| >3510 drinks |
44/65 |
0.74 |
0.47–1.17 |
63/91 |
0.82 |
0.55–1.22 |
39 |
0.70 |
0.47–1.06 |
29 |
1.02 |
0.63–1.63 |
|
Drinking at <20 years | ||||||||||||
| No | 370/391 | Ref | 358/369 | Ref | 293 | Ref | 159 | Ref | ||||
| Yes | 38/72 | 0.60 | 0.38–0.94 | 37/55 | 0.74 | 0.46–1.20 | 30 | 0.64 | 0.41–0.99 | 16 | 0.61 | 0.34–1.07 |
Abbreviations: AA= African-American; BMI=body mass index; Ca=case; CI=confidence interval; Co=control; ER= oestrogen receptor; HRT= hormone replacement therapy; OC=oral contraceptive; OR=odds ratio; PR, progesterone receptor.
ORs are adjusted for age, ethnicity, country of origin, education, age at menarche, age at menopause (only for postmenopausal women), menopausal status (for analyses by hormone receptor status), parity, age at first birth, breastfeeding status, family history of breast cancer, HRT use, OC use, history of benign breast disease, total energy intake, BMI.