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. 2013 Sep 17;109(7):1775–1781. doi: 10.1038/bjc.2013.575

Table 1. Pharmacokinetic parameters for aerosol and systemic delivery of 5-Aza.

 
 AUC (h × ng ml−1)
 Half-life (h)
 Concentrationmax (ng ml−1)
Delivery route Plasma Lung Plasma Lung Plasma Lung
Systemic 19 128 1082 0.42 0.14 15 492 2147
Aerosol 1887 8460 1.24 1.84 893 7883

Abbreviations: 5-Aza=5-azacytidine; AUC=area under the curve; Max=maximum.