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. Author manuscript; available in PMC: 2013 Oct 4.
Published in final edited form as: Nat Rev Clin Oncol. 2013 Mar 5;10(4):225–234. doi: 10.1038/nrclinonc.2013.30

Figure 2.

Figure 2

Radionuclide imaging of a patient with castration-resistant prostate cancera | Tc-99m bone scan, b | FDG–PET, c | NaF–PET. Since the three scans are measuring different aspects of osseous metastases, biomarkers unique to each modality must be developed, analytically validated, and tested independently and prospectively before they achieve clinical validity. Abbreviation: FDG, fluorodeoxyglucose.