Fig. 2.

Molecular network candidates in soft tissue and bone. A, Venn diagram illustrating the overlap between differentially expressed proteins (Table I) identified in soft tissue and bone after tooth extraction. B, canonical overlapping pathways of proteins identified in soft tissue. C, canonical overlapping pathways of proteins identified in bone. Each network comprised arrangements of at least two molecules. The rectangles outlined by solid lines indicate unique networks in soft tissue or bone; those outlined by dotted lines indicate common networks in soft tissue and bone. ERK5, mitogen-activated protein kinase 7 (MAPK7); p70S6K, p70 ribosomal S6 kinase; IGF-1, insulin-like growth factor 1; LXR/RXR, liver X receptor/retinoid X receptor.