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. 2013 Oct 4;8(10):e77219. doi: 10.1371/journal.pone.0077219

Table 1. Top functional annotation terms of the 60 differentially expressed genes.

Terms Ratio (%) P value Benjamini Genes
Overexpressed (n=26) GO:0031224 ~ intrinsic to membrane 50.0 0.010 0.363 TMEM95, NRP1, SCN3A, PCDH19, FAM57B, NTRK3, SSTR3, UCP3, GIPR, DPEP3, TMTC3, IGSF9, GPR12
GO:0030516 ~ regulation of axon extension 7.7 0.023 0.995 NTRK3, NRP1
GO:0016021 ~ integral to membrane 46.2 0.025 0.454 NTRK3, NRP1, TMEM95, SSTR3, UCP3, SCN3A, GIPR, TMTC3, IGSF9, PCDH19, GPR12, FAM57B
GO:0019932 ~ second-messenger-mediated signaling 11.5 0.031 0.971 SSTR3, GIPR, HIST1H4E
GO:0016358 ~ dendrite development 7.7 0.041 0.957 NRP1, IGSF9
Underexpressed (n=34) GO:0034728 ~ nucleosome organization 8.8 0.006 0.371 SET, NAP1L1, HIST1H3I
GO:0006325 ~ chromatin organization 11.8 0.011 0.388 SET, MORF4, NAP1L1, HIST1H3I
GO:0006350 ~ transcription 20.6 0.037 0.729 SCRT2, NACC1, PTGER3, MORF4, FOXC2, NFE2L1, SOX8
GO:0065003 ~ macromolecular complex assembly 11.8 0.048 0.784 NACC1, SET, NAP1L1, HIST1H3I
GO:0008009 ~ chemokine activity 5.9 0.055 0.935 CXCL5, CKLF

Bold font indicates cancer-related genes according to the Ingenuity knowledge database.