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. 2013 Oct 4;8(10):e76129. doi: 10.1371/journal.pone.0076129

Figure 5. Heat acclimation induces basal N-cadherin and post injury detachment of the cadherin-catenin complex.

Figure 5

Representative western blots of N cadherin, showing significant basal induction of N cadherin which lasts up to 6(HA) as compared with normothermic mice (NT) (A). β-catenin was immunoprecipitated (IP) with protein A beads and separated on SDS-PAGE gels. Immunoblotting (IB) of N cadherin indicates disassociation of cadherin-catenin complex in injured HA mice. (−) Immunoprecipitation of non β-catenin related protein (Bcl-xL) with the same beads. (+) input from non immunoprecipitation blot of 60 µg protein from injured HA brain (B). Values represent the mean ± SEM. n = 5–6 per group. *p<0.05 vs. NT mice, **p<0.05 vs. sham mice, within the same group.