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. 2013 Oct 4;8(10):e77182. doi: 10.1371/journal.pone.0077182

Figure 5. Effect of EPO on glutamate-induced LDH release from APC.

Figure 5

(A) LDH-release from APC on DIV7 upon normoxia with and without exposure to 1mM Glu (+Glu vs. –Glu) and treatment of 1U/ml (1UE) and 5U/ml (5U E) EPO. (B) LDH release from APC on DIV7 upon hypoxia; (C) LDH-release from APC on DIV 14 under normoxia; (D) LDH-release from APC on DIV14 under hypoxia; (E) LDH-release from APC on DIV21 under normoxia; (F) LDH-release from APC on DIV21 under hypoxia. Application of 1mM Glu (+Glu in A-F) increased the LDH release from astroglia into the culture supernatant when compared with control without glutamate (-Glu in A-F). *, p<0.05, **, p<0.01, ***, p<0.001.