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. 2013 Oct 4;8(10):e76283. doi: 10.1371/journal.pone.0076283

Figure 2. Ps. aeruginosa filtrate reduces transepithelial resistance and enhances paracellular glucose flux across CF epithelium to a greater extent than non-CF epithelium.

Figure 2

A: Transepithelial resistance (RT) across non-CF and CF HBE monolayers, in the presence and absence of Ps. aeruginosa filtrate (Ps. a). n = 6 in each group, obtained using cells from 3 different non-CF and CF donors assayed in 2 separate experiments. * p<0.05, *** p<0.001. B: Basolateral-to-apical paracellular L-glucose (14C-L-glucose) flux across untreated non-CF and CF HBE monolayers. n = 4 in each group, obtained using cells from 2 different non-CF and CF donors assayed across 4 separate experiments. C: Basolateral-to-apical paracellular L-glucose (14C-L-glucose) flux across non-CF and CF HBE monolayers in the presence of Ps. aeruginosa filtrate (Ps. a). n = 4 in each group, obtained using cells from 2 different non-CF and CF donors assayed across 4 separate experiments. ** p<0.01.