Table 3.
Cramer-Rao Lower Bound for Each Metabolite in 2 Regions of Interest at Baseline and at 4 Weeks in the FEP Group and the Control Group
| Variable | Mean (SD)
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| At Baseline
|
At 4 wk
|
|||||||||||
| Glu | Glx | NAA | GPC + PCh | Ins | Cr + PCr | Glu | Glx | NAA | GPC + PCh | Ins | Cr + PCr | |
| Right associative striatum | ||||||||||||
|
| ||||||||||||
| FEP group | 6.67 (0.92) | 8.38 (1.28) | 3.38 (1.01) | 3.58 (0.72) | 8.33 (1.34) | 3.00 (0.51) | 7.17 (2.33) | 8.79 (2.00) | 4.08 (1.25) | 4.00 (0.93) | 9.58 (2.52) | 3.29 (0.95) |
|
| ||||||||||||
| Control group | 6.83 (1.04) | 8.33 (1.64) | 4.22 (1.86) | 4.00 (0.90) | 9.61 (2.06)a | 3.28 (0.57) | 6.56 (0.86) | 8.17 (1.76) | 3.33 (1.19) | 3.72 (0.46) | 9.78 (2.98) | 2.94 (0.42) |
|
| ||||||||||||
| Right cerebellar cortex | ||||||||||||
|
| ||||||||||||
| FEP group | 7.00 (1.13)b | 8.58 (1.81)b | 4.88 (1.30) | 3.42 (1.25) | 6.38 (2.31) | 2.58 (1.32) | 7.42 (1.71) | 8.88 (1.96)b | 4.88 (1.03) | 3.33 (0.56) | 6.29 (1.23) | 2.58 (0.72) |
|
| ||||||||||||
| Control group | 7.61 (1.50) | 9.39 (1.85) | 4.72 (1.32) | 3.44 (0.51) | 6.39 (0.98) | 2.39 (0.50) | 7.11 (1.08) | 8.33 (1.32) | 4.39 (0.85) | 3.33 (0.48) | 5.89 (1.08) | 2.33 (0.48) |
Abbreviations: Cr + PCr, creatine-containing compounds; FEP, first-episode psychosis; Glu, glutamate; Glx, glutamate + glutamine; GPC + PCh, choline-containing compounds; Ins, myo-inositol; NAA, N-acetylaspartate.
a
P < .05.
b
One spectrum was rejected because of a Cramer-Rao lower bound exceeding 20%.