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. 2013 Oct 4;8(10):e77012. doi: 10.1371/journal.pone.0077012

Figure 8. Stratifin association with plakophilin-3 limits the exchange of plakophilin-3 with the desmosomal plaque.

Figure 8

The association of stratifin with plakophilin-3 occurs through phosphorylation of serine 285 and limits the ability of cytoplasmic plakophilin-3 to exchange with the plakophilin-3 present at the desmosome. Decreased plakophilin-3 exchange at the desmosome is correlated with increased desmosomal adhesion and decreased cell migration.