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. 2013 Oct 4;8(10):e75182. doi: 10.1371/journal.pone.0075182

Table 3. Residues lying within 4 Å distance of docked Compounds.

Vinblastine Val353, Phe351, Gly354, Ile385, Asn249, Asn329, Pro352, Lys326 of α – subunit of tubulin dimer. Asp179, Pro175, Ser178, Lys176, Val177, Tyr210, Tyr 224, Pro222, Thr223, Thr221, Leu227 of β- subunit of tubulin dimer.
Ansamitocin P3:Position A Val353, Pro325, Val328, Asn329, Ile332, Ala333, Lys336, Phe343, Phe351, Gly350, Thr349, Pro348 of α – subunit of tubulin dimer.Asp179, Pro175, Ser178, Lys176, Val177 of β- subunit of tubulin dimer.
Ansamitocin P3:Position B Lys326, Asn329, Pro325, Ile332, Val328, Tyr357, Ile355, Tyr319, Gly354, Val353, Asp249, Leu248 of α – subunit of tubulin dimer.Thr220, Phe214, Lys176, Tyr210, Pro222, Val177, Ser178, Asp179 of β- subunit of tubulin dimer.
Maytansine Val353, Gly354, Ile355, Asn249, Ala247, Leu248 of α – subunit of tubulin dimer.Asp101, Pro222, Ser178, Gly11, Gly225, Val177, Tyr224, Thr223), Thr221 of β- subunit of tubulin dimer.