Table 2.
Risk of bias summary of controlled trials of bupropion versus venlafaxine in major depressive disorder
| Study | Issues of bias
|
|||||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
| Thase37 | U | L | L | L | U | L | L | L |
| Hewett40 | U | L | L | L | U | L | L | L |
| Hewett41 | U | L | L | L | U | L | L | L |
Notes: 1 = Adequate sequence generation; 2 = Allocation concealment; 3 = Blinding (subjective outcome); 4 = Dropout data addressed; 5 = Free of selective reporting; 6 = Free of other bias; 7 = Baseline similarity; 8 = Itention-to-treat analysis or modifed intention-to-treat analysis.
Abbreviations: L, low risk of bias; U, unclear risk of bias.