Figure 8. Hepcidin quantification by WCX-TOF MS in human samples that were pre-incubated with 0, 5 or 10 nM of PRS-080 to block binding of hepcidin to the WCX beads.

Decrease in hepcidin concentration was determined by measurement of 6 different samples, with total hepcidin concentrations between 10 and 40-080. Dotted line indicates the theoretically expected 1∶1 ratio. Description of the line: Y = 0.655X+0.013 (R² = 0.9373).