Table 3.
Baseline | 3 months FU | 6 months FU | 12 months FU | Two-way ANOVA | ||||||
---|---|---|---|---|---|---|---|---|---|---|
MSC (n = 8) | Control (n = 38) | P value* | MSC (n = 8) | Control (n = 38) | MSC (n = 8) | Control (n = 38) | MSC (n = 8) | Control (n = 38) | P value** | |
LVESV (mL) | 50 ± 9 | 58 ± 18 | 0.21 | 49 ± 14 | 58 ± 22 | 47 ± 11 | 54 ± 23 | 45 ± 14 | 52 ± 26 | 0.87 |
LVEDV (mL) | 95 ± 16 | 105 ± 29 | 0.36 | 101 ± 26 | 112 ± 28 | 102 ± 20 | 110 ± 24 | 104 ± 30 | 108 ± 28 | 0.46 |
LVEF (%) | 48 ± 2 | 45 ± 9 | 0.38 | 52 ± 2 | 49 ± 11 | 54 ± 4 | 50 ± 10 | 57 ± 3 | 50 ± 12 | 0.28 |
WMSI | 1.6 ± 0.2 | 1.7 ± 0.3 | 0.28 | 1.4 ± 0.3 | 1.5 ± 0.3 | 1.4 ± 0.5 | 1.4 ± 0.3 | 1.2 ± 0.1 | 1.4 ± 0.3 | 0.20 |
LVESV left ventricular end-systolic volumes, LVEDV left ventricular end-diastolic volumes, LVEF left ventricular ejection fractions, WMSI Wall Motion Score Index, FU follow-up
*P values are given for the comparison of parameters between controls and MSC-treated patients at baseline
** P values are given for the comparison of parameters between controls and MSC-treated patients during 12 months follow-up