Table 3.
Performance on CAMCI tasks
| HIV serostatus | HIV+ | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| HIV− | HIV+ | p value | HIV− | NML | ANI | MND | HAD | p value | |
| Total n | 38 | 114 | 38 | 16 | 37 | 22 | 39 | ||
| Simple Reaction Time task, mean score/max score (SD) | 31.5/32 (1.7) | 31.8/32 (0.5) | 0.13 | 31.5/32 (1.7) | 32.0/32 (0.3) | 31.9/32 (0.3) | 31.6/32 (0.7) | 31.7/32 (0.5) | 0.37 |
| Reaction time in milliseconds, mean (SD) | 548.9 (166.6) | 607.4 (137.3) | 0.03 | 548.9 (166.6) | 575.1 (135.2) | 592.5 (110.2) | 618.2 (152.1) | 628.8 (152.8) | 0.16 |
| Reaction time in milliseconds, median (SD) | 520.8 (163.9) | 585.4 (136.7) | 0.02 | 520.8 (163.9) | 550.3 (132.6) | 572.6 (114.6) | 593.2 (150.8) | 607.6 (149.5) | 0.10 |
| Go/No Go, Rule 1, mean score/max score (SD) | 9.5/10 (1.0) | 9.0/10 (1.9) | 0.12 | 9.5/10 (1.0) | 9.7/10 (0.5) | 9.0/10 (1.6) | 8.7/10 (2.2) | 8.8/10 (2.3) | 0.22 |
| Go/No Go, Rule 2, mean score/max score (SD) | 9.5/10 (0.9) | 9.0/10 (2.1) | 0.17 | 9.5/10 (0.9) | 9.5/10 (1.0) | 9.3/10 (1.5) | 8.2/10 (2.7) | 9/10 (2.4) | 0.09 |
| Recurring Pictures, mean score/max score (SD) | 16.7/20 (3.2) | 15.6/21 (4.0) | 0.13 | 16.7/20 (3.2) | 15.3/21 (4.0) | 15.5/21 (4.0) | 16.1/21 (4.1) | 15.7/21 (4.0) | 0.60 |
| Forward Digit Span Score, mean score/max score (SD) | 7.6/10 (1.8) | 6.8/10 (1.8) | 0.02 | 7.6/10 (1.8) | 7.8/10 (1.9) | 6.9/10 (1.9) | 6.8/10 (1.7) | 6.2/10 (1.7) | 0.01 |
| Forward Digit Span Size, mean score/max score (SD) | 6.3/7 (0.8) | 5.8/7 (1.1) | 0.01 | 6.3/7 (0.8) | 6.3/7 (1) | 5.9/7 (1.1) | 6/7 (0.9) | 5.4/7 (1.1) | 0.00 |
| Backward Digit Span Score, mean score/max score (SD) | 6.2/10 (2.4) | 4.7/10 (2.2) | 0.00 | 6.2/10 (2.4) | 5.7/10 (2.7) | 5.1/10 (2.1) | 3.9/10 (1.5) | 4.4/10 (2.1) | 0.00 |
| Backward Digit Span Size, mean score/max score (SD) | 4.7/6 (1.2) | 3.8/6 (1.3) | 0.00 | 4.7/6 (1.2) | 4.4/6 (1.4) | 4/6 (1.3) | 3.2/6 (1.01) | 3.7/6 (1.2) | 0.00 |
| Word Recall, mean score/max score (SD) | 3.7/5 (1.3) | 2.4/5 (1.3) | <0.01 | 3.7/5 (1.3) | 2.5/5 (1.2) | 2.8/5 (1.4) | 2.4/5 (1.1) | 2.1/5 (1.4) | <0.01 |
| Shopping Trip Directions, mean score/max score (SD) | 16.1/18 (2.2) | 15.1/18 (3.2) | 0.05 | 16.1/18 (2.2) | 14.4/18 (4.8) | 16.1/18 (2.7) | 14.7/18 (2.8) | 14.5/18 (2.8) | 0.03 |
| Shopping List, mean score/max score (SD) | 3.7/4 (0.6) | 3.1/4 (1.1) | 0.01 | 3.7/4 (0.6) | 3.3/4 (1.1) | 3.3/4 (1.1) | 3.2/4 (1.1) | 2.87/4 (1.17) | 0.02 |
| Incidental Recall, mean score/max score (SD) | 2.3/5 (1.3) | 2.0/5 (0.9) | 0.09 | 2.3/5 (1.3) | 2.2/5 (1.0) | 1.9/5 (1.0) | 1.8/5 (0.7) | 2.1/5 (1.0) | 0.32 |
| ATM, mean score/max score (SD) | 5.8/7 (2.0) | 5.2/7 (1.9) | 0.12 | 5.8/7 (2.0) | 5.1/7 (2.0) | 5.4/7 (1.7) | 5.4/7 (1.8) | 5.2/7 (2.0) | 0.59 |
| Errands—bank, no. (%) | 30 (79.0) | 53 (46.5) | 0.00 | 30 (79.0) | 9 (56.3) | 17 (46.0) | 10 (46.0) | 17 (43.6) | 0.01 |
| Errands—post office, no. (%) | 30 (79.0) | 56 (49.1) | 0.00 | 30 (79.0) | 9 (56.3) | 17 (46.0) | 10 (46.0) | 20 (51.3) | 0.03 |
Comparison of HIV− and HIV+ subjects classified into HAND criteria on all CAMCI neuropsychological and functional tasks. Differences were noted between the groups on tasks of Forward and Backward Digit span and Word Recall
SD standard deviation, ATM automatic teller machine, NML normal cognition, ANI asymptomatic neurocognitive impairment, MND minor neurocognitive disorder, HAD HIV-associated dementia