Fig. 7.

Ultrasound imaging of the LCA in rat and improvement in CFVR with exercise. Upper panel (a–c): Color Doppler images from baseline (a), low dose (b), towards high dose of adenosine (c) with corresponding pulsed wave Doppler images (mid-panel:d-f). CFVR and adenosine dose–response curves for voluntarily exercising spontaneous hypertensive rats (solid line) vs non-exercising controls (dashed line) (g). As evident, voluntary exercising rats had higher CFVR compared with controls after 6 weeks. **p < 0.01. Adapted from [79] with permission