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Endothelial nitric oxide synthase (eNOS) immunohistochemistry in the brain cortex after transient focal ischemia. Endothelial nitric oxide synthase expression in the parenchymal small vessels increased in the middle cerebral artery (MCA) core, MCA peripheral area, and anterior cerebral artery (ACA) area, compared with the contralateral side (A). Signals of eNOS also increased in the larger vessels on the brain surface (B). Scale bar, 100 μm in panels A and B.
