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Operationalizing quality of life using an area under the curve (AUC) approach. Example: This patient has 5 visits in total. He has 2 visits within the first 30 days and 3 visits after 30 days. Here is how AUC gets calculated: Area 1=(0.6+0.4)*(55−30)/2=12.5 (Trapezoidal Rule); Area 2=(0.2+0.4)*(100−55)/2=13.5 (Trapezoidal Rule); Area 3=0.2*(120−100)=4 (Rectangle); Maximum possible area after 30 days=(120−30)*1=90; AUC=(area1+area2+area3)/(maximum area)=(12.5+13.5+4)/90=30/90=0.33.
