Table 1.

Sex of Offspring of Cancer Survivors (Stratified by Type of Treatment Received) and of Sibling Controls

	No. of Offspring ofSurvivors Who Receiveda,b			No. of Offspring ofSurvivors Who Receivedc
Sex of OffspringStratified bySex of Subjects	PotentiallyMutagenicTherapy	Less- orNonmutagenicTherapy	No. of Offspring of Sibling Controlsb	PotentiallyMutagenicTherapy	Less- orNonmutagenicTherapy
Male subjects:
Male offspring	100	344	1,022	137	529
Female offspring	94	340	1,021	141	522
Subtotal (sex ratio)	194 (1.06)	684 (1.01)	2,043 (1.00)	278 (0.97)	1,051 (1.01)
Female subjects:
Male offspring	98	513	1,278	140	794
Female offspring	116	498	1,223	165	731
Subtotal (sex ratio)	214 (0.84)	1,011 (1.03)	2,501 (1.04)	305 (0.85)	1,525 (1.09)
Total	408	1,695	4,544	583	2,576

^aThe sum of offspring of survivors treated with potentially mutagenic therapy and those treated with less- or nonmutagenic therapy is slightly less than the total number of offspring of the survivors, because the site of radiotherapy, in some patients, was not known.

^bData on offspring of subjects from original study (Byrne et al. 1998).

^cCombined data (Hawkins 1991; Byrne et al. 1998).