Table 5.

Association between smoking cessation, weight change and coronary heart disease (CHD) events

		No diabetes
	Smokers (ref)	Former smokers		Non smokers
		Quit for ≤ 4 y	Quit for > 4 y
Person-exams	1924	591	3761	3392
No. of CHD events	48	10	45	21
Age-, sex-adjusted IR of	5.12	3.93	2.32	1.34
CHD/100 person-exams
(95% CI)	(2.33-10.75)	(1.12-12-28)	(1.18-4.55)	(0.06-3.24)
Age-, sex-adjusted HR
(95% CI)
Age-, sex-adjusted HR
	1	0.63 (0.22-1.83)	0.32 (0.18-0.56)	0.19 (0.09-0.38)
(95% CI)
CVD risk factors-
	1	0.58 (0.20-1.68)	0.29 (0.16-0.52)	0.17 (0.08-0.36)
adjusted† HR(95% CI)
CVD risk factors-+
weight change-adjusted	1	0.61 (0.21-1.78)	0.29 (0.16-0.52)	0.17 (0.08-0.36)
HR (95% CI)
		Diabetes
	Smokers (ref)	Former smokers		Non smokers
		Quit for ≤ 4 y	Quit for > 4 y
Person-exams, n	279	92	603	506
No. of CHD events	10	3	16	7
Age-, sex-adjusted IR of	9.30	5.49	4.84	3.71
CHD/100 person-exams
(95% CI)	(7.67-11.22)	(3.78-7.88)	(4.06-5.77)	(2.99-4.60)
Age-Sex-adjusted OR
	1	0.40 (0.05-3.17)	0.40 (0.16-1.02)	0.15 (0.04-0.52)
(95% CI)
CVD risk factors-
	1	0.37 (0.05-3.01)	0.42 (0.16-1.10)	0.15 (0.04-0.57)
adjusted† HR(95% CI)
CVD risk factors-+
weight change-adjusted	1	0.36 (0.04-2.97)	0.42 (0.16-1.10)	0.15 (0.04-0.57)
OR (95% CI)

No. = number, CHD = coronary heart disease = myocardial infarction + coronary death, HR = Hazard Ratio, CI = Confidence Interval, BMI = body-mass index, ref = reference

^†Adjusted for age, sex, alcohol consumption, self-reported family history of diabetes, systolic, blood pressure, HDL-cholesterol, LDL-cholesterol, Triglycerides, baseline BMI, cholesterol lowering treatment, anti-hypertension treatment