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. Author manuscript; available in PMC: 2013 Oct 5.
Published in final edited form as: Circulation. 2009 Jan 12;119(3):408–416. doi: 10.1161/CIRCULATIONAHA.108.822072

Figure 7. Unloaded cell shortening, and calcium handling of cardiomyocytes isolated from WT and PDE5-TG at 10 weeks after myocardial infarction.

Figure 7

Unloaded cell shortening (L/L0) at different stimulation frequencies are similar for both genotypes (A), while kinetics of shortening differ significantly with longer time to peak shortening (B) and half-relaxation times (C) in PDE5-TG (n=19 cells) versus WT (n=33 cells). Diastolic resting Ca2+ concentrations (D) and amplitudes of Ca2+ (E) transients are significantly greater in cardiomyocytes isolated from PDE5-TG (n=15 cells) versus WT (n=21 cells). *P<0.05 versus WT.