Table 6.
Multivariable analyses of prognostic factors for retransplantation, graft survival, and overall survival following liver transplantation for hepatocellular carcinoma
| Factors associated with retransplantation | ||
|---|---|---|
| Odds ratio (95% CI) | P-value | |
| Age | 0.98 (0.96–0.99) | 0.003 |
| Viral status | <0.001 | |
| HBV−/HCV− | 1.00 | |
| HBV+/HCV−a | 0.57 (0.30–1.08) | 0.087 |
| HBV−/HCV+a | 1.03 (0.77–1.36) | 0.859 |
| HBV+/HCV+ | 0.57 (0.18–1.83) | 0.342 |
| Factors associated with graft survival | ||
|---|---|---|
| Hazard ratio (95% CI) | P-value | |
| Age | 1.02 (1.01–1.02) | <0.001 |
| MELD score | 1.02 (1.01–1.02) | <0.001 |
| Diabetes | 0.019 | |
| No | 1.00 | |
| Yes | 1.14 (1.02–1.27) | |
| Viral status | <0.001 | |
| HBV−/HCV− | 1.00 | |
| HBV+/HCV−b | 0.76 (0.59–0.98) | 0.033 |
| HBV−/HCV+b | 1.25 (1.11–1.41) | <0.001 |
| HBV+/HCV+ | 1.03 (0.70–1.51) | 0.883 |
| Factors associated with overall survival | ||
|---|---|---|
| Hazard ratio (95% CI) | P-value | |
| Age | 1.02 (1.02–1.03) | <0.001 |
| MELD score | 1.02 (1.01–1.03) | <0.001 |
| Race | 0.022 | |
| White | 1.00 | |
| African-American | 1.22 (1.02–1.46) | 0.028 |
| Asian | 0.89 (0.70–1.13) | 0.343 |
| Hispanic | 0.90 (0.77–1.05) | 0.171 |
| Other | 0.65 (0.37–1.12) | 0.120 |
| Diabetes | 0.012 | |
| No | 1.00 | |
| Yes | 1.16 (1.03–1.31) | |
| Viral status | <0.001 | |
| HBV−/HCV− | 1.00 | |
| HBV+/HCV−c | 0.85 (0.63–1.13) | 0.263 |
| HBV−/HCV+c | 1.29 (1.13–1.47) | <0.001 |
| HBV+/HCV+ | 1.18 (0.79–1.76) | 0.424 |
95% CI, 95% confidence interval; HBV, hepatitis B virus; HCV, hepatitis C virus; MELD, Model for End-stage Liver Disease.
a
Significantly different odds ratios (P = 0.005) when directly compared.
b
Significantly different hazard ratios (P < 0.001) when directly compared.
c
Significantly different hazard ratios (P = 0.003) when directly compared.