Table 1.
Patient demographics
| Variable | Value |
|---|---|
| Gender | |
| Male | 466 (58%) |
| Female | 341 (42%) |
| Age | |
| Median age (years, range) | 63 (23–89) |
| >70 years old | 200 (25%) |
| Primary site | |
| Colon | 582 (72%) |
| Rectum | 225 (28%) |
| T stage of primary tumour | |
| 1 | 25 (3%) |
| 2 | 104 (13%) |
| 3 | 586 (73%) |
| 4 | 40 (5%) |
| Unknown | 52 (6%) |
| N stage of primary tumour | |
| N0 | 325 (40%) |
| N1,2 | 482 (60%) |
| Lymphovascular invasion of primary tumour | |
| Present | 356 (44%) |
| Absent | 199 (25%) |
| Unknown | 252 (31%) |
| Perineural invasion of primary tumour | |
| Present | 389 (48%) |
| Absent | 96 (12%) |
| Unknown | 322 (40%) |
| Tumour grade of primary tumour | |
| Low | 21 (3%) |
| Moderate | 635 (79%) |
| Poor | 67 (8%) |
| Unknown | 84 (10%) |
| Disease-free interval, months | |
| 0–12 | 444 (55%) |
| >12 | 363 (45%) |
| Size of largest metastasis, cm | |
| <5 | 554 (69%) |
| ≥5 | 253 (31%) |
| Number of liver metastases | |
| 1 | 397 (49%) |
| >1 | 410 (51%) |
| Pre-operative CEA level, ng/ml | |
| <200 | 642 (80%) |
| ≥200 | 76 (9%) |
| Unknown | 89 (11%) |
| Clinical Risk Score | |
| 0 | 55 (7%) |
| 1 | 239 (30%) |
| 2 | 267 (33%) |
| 3 | 184 (23%) |
| 4 | 51 (6%) |
| 5 | 11 (1%) |
| Clinical Risk Score: low versus high | |
| Low (0–2) | 561 (70%) |
| High (3–5) | 246 (30%) |
| Extent of liver resection | |
| Minor | 319 (40%) |
| Major | 488 (60%) |
| Extrahepatic disease resected | |
| Yes | 32 (4%) |
| No | 775 (96%) |
| Peri-operative chemotherapy | |
| Neoadjuvant | 179 (22%) |
| Adjuvant | |
| Systemic | 654 (81%) |
| HAI + systemic | 208 (26%) |
CEA, carcinoembryonic antigen; HAI, hepatic arterial infusion.