Table 1.
Baseline Demographics and laboratory Data of Study Patients
| Variable | Eptifibatide (N = 9) | Placebo (N = 4) |
|---|---|---|
|
| ||
| Age (years) [Range] | 25 (22–48) | 31 (24–50) |
|
| ||
| Gender | ||
| (M) | 3 (33) | 1 (25) |
| (F) | 6 (67) | 3 (75) |
|
| ||
| Genotype | ||
| (SS) | 6 (67) | 4 (100) |
| (Sβ0) | 2 (22) | - |
| (SC) | 1 (11) | - |
|
| ||
| Weight (Kg) | 72.1 (56.7 – 100.1) | 59.0 (56.0 – 62.4) |
|
| ||
| White Blood Cell Count (× 109/L) | 11.3 (7.7 – 19.1) | 14.5 (11.9 – 26.3) |
|
| ||
| Absolute Neutrophil Count (× 109/L) | 7.4 (3.0 – 14.4) | 8.9 (4.0 – 21.4) |
|
| ||
| Hemoglobin (g/dL) | 8.1 (5.9 – 10.6) | 7.5 (5.5 – 9.3) |
|
| ||
| Platelet Count (× 109/L) | 521 (96 – 829) | 397 (317 – 519) |
|
| ||
| Hemoglobin F (%) | 9.35 (0.3 – 29.3) | 8.6 (7.3 – 17.5) |
|
| ||
| Creatinine (mg/dL) | 0.7 (0.38 – 1.09) | 0.53 (0.45 – 0.80) |
|
| ||
| Alanine Transaminase (U/L) | 29 (7 – 64) | 42.5 (31 – 65) |
|
| ||
| Lactate Dehydrogenase (U/L) | 684 (435 – 1235) | 981.5 (719 – 1574) |
|
| ||
| Total Bilirubin (mg/dL) | 1.9 (0.7 – 2.8) | 2.45 (1.6 – 10.7) |
Median (Min-Max) provided for continuous variables. N (percent) for categorical variables