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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Mol Cell Neurosci. 2013 May 25;0:201–211. doi: 10.1016/j.mcn.2013.05.003

Table 1.

Insertion of native and recombinant γ2- and δ subunit-containing GABARs at the surface membrane.

Receptor type 5 min 15 min 30 min 60 min Total surface expressed
Native γ2- GABARs 0.04 ± 0.02* 0.085 ± 0.028* 0.11 ± 0.03 0.09 ± 0.03* 0.16 ± 0.05
α1β3t-γ2 - 0.035 ± 0.01* 0.050 ± 0.007* 0.051± 0.007* 0.11 ± 0.005
α4β3t-γ2 - 0.027 ± 0.006* 0.079 ± 0.011 0.09 ± 0.009 0.15 ± 0.02
30 min 60 min 120 min 180 min Total surface expressed
Native δ-GABARs 0.04 ± 0.02* 0.08 ± 0.03* 0.11 ± 0.02* 0.13 ± 0.06* 0.20 ± 0.04
α1β3t-δ 0.023 ± 0.004* 0.024 ± 0.005* 0.035 ± 0.005* 0.041 ± 0.007* 0.097 ± 0.01
α4β3t-δ 0.018 ± 0.004* 0.033 ± 0.005 0.043 ± 0.008 0.042 ± 0.004 0.077 ± 0.01

Insertion of native receptors expressed in cultured hippocampal neurons and recombinant receptors expressed in HEK293 cells. Values represent surface immunoreactive area normalized to the cell area, mean ± SE from 30–36 cells/ 4–7 replicates each.

*

p<0.05 vs total surface expressed receptors.