. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Cancer Prev Res (Phila). 2013 Sep 26;6(10):1015–1025. doi: 10.1158/1940-6207.CAPR-13-0172

Table 1.

Treatment plan showing group of hamsters treated with unmodified (Set 1) and SLN modified nanoparticle (Set 2) forms of chemopreventive agents ASP, CUR and SFN at various doses.

Set 1
	Group	Treatment plan	Dose, mg/kg
T1	Saline control	Saline (control)	0
T2	BOP control	BOP	35 (1^st week) / 20 (next 4 weeks)
T3	Low dose ACS	ASP+CUR+SFN	20 + 45 + 1.6
T4	Medium dose ACS	ASP+CUR+SFN	70 + 150 + 5
T5	High dose ACS	ASP+CUR+SFN	200 + 450 + 16
Set 2
T6	Saline control	Saline (Control)	0
T7	Blank SLN control	Blank SLN (Vehicle control)	0
T8	BOP control	BOP	35(1^st week) / 20(next 4 weeks)
T9	Low dose SLN ACS	ASP+CUR+SFN	2 + 4.5 + 0.16
T10	Medium dose SLN ACS	ASP+CUR+SFN	7 + 15 + 0.5
T11	High dose SLN ACS	ASP+CUR+SFN	20 + 45 + 1.6

Abbreviations: ASP, aspirin; CUR, curcumin; SFN, sulforaphane; BOP, N-nitrosobis (2-oxopropyl) amine; SLN, solid lipid nanoparticles.