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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Hepatology. 2013 Oct 11;58(6):10.1002/hep.26547. doi: 10.1002/hep.26547

Figure 5. Hepatic glutathione levels in wild type and RIP3-deficient mice.

Figure 5

Wild type (RIP3+/+) and RIP3−/− mice were treated with 300 mg/kg APAP or saline. At 6 h after APAP, total glutathione (GSH+GSSG) (A) and GSSG (B) levels were determined and the GSSG-to-GSH ratio (C) was calculated. Data represent means ± SE of n= 3–5. *P<0.05 (compared to CTRL). #P<0.05 (compared to RIP3+/+ APAP).