Table 1.
Demographic characteristics of participants.
Abbreviations: HC = healthy controls; aMCI = amnestic Mild Cognitive Impairment; AD = Alzheimer's disease; SD = semantic dementia; IQR = interquartile range; MMSE = mini-mental state examination; ANOVA = Analysis of variance.
All variables were compared using non-parametric tests.
a: Mattis scores were lower in AD and SD groups as compared to HC and aMCI but no difference was found between AD and SD.
| HC (n = 40) | aMCI (n = 17) | AD (n = 18) | SD (n = 8) | Group comparison | |
|---|---|---|---|---|---|
| Age median (IQR) |
66 (56, 72) | 72 (69, 75) | 66 (58, 76) | 62.5 (59.5, 65.5) | pANOVA = 0.027 aMCI > HC; aMCI > SD |
| Gender females: n (%) |
23 (58%) | 9 (53%) | 12 (67%) | 5 (63%) | pChi-squared = 0.86 |
| Years of education median (IQR) |
12 (9.5, 15) | 10 (8, 12) | 10 (7, 14) | 12 (5.8, 15.5) | pANOVA = 0.19 |
| MMSE median (IQR) |
30 (29, 30) | 27 (26, 28) | 20.5 (20, 24) | – | pANOVA < 0.001 HC > aMCI > AD |
| Mattis median (IQR) |
143 (142, 144) | 137 (134, 138) | 123 (114, 128) | 118 (111, 125.5) | pANOVA < 0.001 HC > aMCI > AD, SDa |