Fig. 2.

Effects of age and gender on the T1-weighted image. The effects of age and gender are color-coded on the 177 areas of the atlas space. The red represents positively weighted areas and the blue represents negatively weighted areas. Weights are relative, and have no applicable units. The images are in radiological convention (R represents the right side). The effect of age was mostly identified around the ventricles. The effect of female gender was found in the left superior temporal, bilateral middle occipital, bilateral subgenual anterior cingulate, and the right prefrontal areas, which were positively weighted, and the left inferior temporal, left precentral, and bilateral superior parietal areas, which were negatively weighted. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)