Table 2.
Regions demonstrating significant differences between the two groups in voxel-wise functional connectivity with the nucleus accumbens seed in each behavioral state.
| Region | L/R | MNI coordinate |
||
|---|---|---|---|---|
| x,y,z | t | z | ||
| Resting-state | ||||
| Positive network | ||||
| Controls > patients | ||||
| Putamen | R | 27, − 21, 3 | 5.05 | 4.6 |
| Parahippocampus | R | 21, − 18, − 18 | 3.77 | 3.59 |
| Posterior insula | L | − 39, 0, − 6 | 3.58 | 3.42 |
| Controls < patients | ||||
| Cerebellum | L | − 21, − 81, − 54 | 4.58 | 4.27 |
| Orbitofrontal cortex | R | 27, 30, − 9 | 4.29 | 4.03 |
| Gain anticipation | ||||
| Controls > patients | ||||
| Amygdala | L | − 33, 9, − 15 | 4.27 | 4.01 |
| Middle frontal cortex | L | − 27, 6, 45 | 3.63 | 3.46 |
| Midbrain (Substantia nigra) | L | 0, − 18, − 12 | 3.29 | 3.16 |
| Controls < patients | ||||
| Calcarine | R | 24, − 69, 15 | 5.07 | 4.66 |
| Cerebellum | R | 15, − 66, 3 | 4.48 | 4.18 |
| Calcarine | L | − 6, − 54, 3 | 4.10 | 3.87 |
| Posterior insula | L | − 39, 0, 12 | 4.06 | 3.83 |
| Cerebellum | L | − 15, − 51, − 12 | 3.74 | 3.56 |
| Posterior insula | R | 45, − 6, 6 | 3.53 | 3.38 |
| Temporal pole | L | − 39, 0, − 18 | 3.35 | 3.22 |
| Loss anticipation | ||||
| Controls > patients | ||||
| Globus pallidus, Amygdala | R | 30, − 18, − 6 | 4.70 | 4.37 |
| Middle temporal cortex | R | 42, − 6, − 21 | 4.55 | 4.24 |
| Thalamus | L | − 3, − 24, 0 | 4.53 | 4.23 |
| Middle temporal cortex | L | − 42, − 30, 0 | 4.33 | 4.06 |
| Thalamus | L | − 3, 0, − 3 | 4.21 | 3.96 |
| Cerebellum | R | 48, − 57, − 36 | 3.85 | 3.66 |
| Inferior frontal cortex | L | − 48, 18, 8 | 3.78 | 3.59 |
| Fusiform | R | 42, − 27, − 21 | 3.68 | 3.51 |
| Cerebellum | L | − 42, − 66, − 27 | 3.67 | 3.50 |
| Amygdala | L | − 33, 6, − 15 | 3.67 | 3.50 |
| Controls < patients | ||||
| Calcarine | R | 24, − 69, 15 | 4.09 | 3.86 |
Abbreviations: L, left; R, right.