Table 5.
Variable | INTRA-AMNIOTIC INFLAMMATION |
P value | |
---|---|---|---|
NO | YES | ||
Umbilical cord | n=20 | n=19 | |
Interleukin-6, pg/mL ¶ | 5.8 [5.1-8.3] | 18.9 [7.6-69.2] | 0.003 |
Erythropoietin, mIU/mL ¶ | 6.9 [5.1-16.8] | 8.6 [2.7-15.2] | 0.911 |
Neonatal metabolic and
cardiovascular status |
n=30 | n=18 | |
Blood urea nitrogen, mg/dL ¶ | 14.0 [10.5-21.5] | 25.5 [21.5-39.0] | < 0.001 |
Creatinine, mg/dL ¶ | 0.8 [0.8-0.9] | 0.8 [0.7-0.9] | 0.742 |
Temperature, °C ¶ | 37.2 [36.9-37.4] | 36.9 [36.9-37.1] | 0.205 |
Mean arterial blood pressure, mmHg ¶ | 35.0 [30.7-38.2] | 29.5 [25.0-32.0] | 0.002 |
Heart rate, beats/minutes ¶ | 162 [150-170] | 170 [164-180] | 0.040 |
Urinary output, cc/kg/hr ¶ | 1.9 [1.3-2.8] | 3.1 [1.1-4.1] | 0.322 |
Intravenous fluids, cc/kg/day ¶ | 76.15 [68.1-85.9] | 74.8 [69.1-91.4] | 0.765 |
Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA.
NBSCU= Newborn Special Care Unit. Intra-amniotic inflammation was defined based on the proteomic Mass Restricted (MR) score. An MR score 0 (zero) indicates “no” inflammation. MR score 3-4 indicates “severe” inflammation (see references 21 & 22).