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. Author manuscript; available in PMC: 2013 Oct 6.
Published in final edited form as: Am J Obstet Gynecol. 2009 Feb;200(2):203.e1–203.11. doi: 10.1016/j.ajog.2008.11.001

Table 5.

Interleukin-6 and Erythropoietin Umbilical cord values for 39 neonates. Cardiovascular and metabolic profiles of the neonates admitted in the NBSCU in the first 24 hours of life (n=48).

Variable INTRA-AMNIOTIC INFLAMMATION
P value
NO YES
Umbilical cord n=20 n=19
Interleukin-6, pg/mL 5.8 [5.1-8.3] 18.9 [7.6-69.2] 0.003
Erythropoietin, mIU/mL 6.9 [5.1-16.8] 8.6 [2.7-15.2] 0.911
Neonatal metabolic and
cardiovascular status
n=30 n=18
Blood urea nitrogen, mg/dL 14.0 [10.5-21.5] 25.5 [21.5-39.0] < 0.001
Creatinine, mg/dL 0.8 [0.8-0.9] 0.8 [0.7-0.9] 0.742
Temperature, °C 37.2 [36.9-37.4] 36.9 [36.9-37.1] 0.205
Mean arterial blood pressure, mmHg 35.0 [30.7-38.2] 29.5 [25.0-32.0] 0.002
Heart rate, beats/minutes 162 [150-170] 170 [164-180] 0.040
Urinary output, cc/kg/hr 1.9 [1.3-2.8] 3.1 [1.1-4.1] 0.322
Intravenous fluids, cc/kg/day 76.15 [68.1-85.9] 74.8 [69.1-91.4] 0.765

Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA.

NBSCU= Newborn Special Care Unit. Intra-amniotic inflammation was defined based on the proteomic Mass Restricted (MR) score. An MR score 0 (zero) indicates “no” inflammation. MR score 3-4 indicates “severe” inflammation (see references 21 & 22).