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. 2013 Oct;23(10):1143–1150. doi: 10.1016/j.euroneuro.2012.12.001

Figure 1.

Figure 1

Meta-analysis of association studies of 5-HTTLPR genotype and SSRI discontinuation stratified by ancestry (European vs. East Asian vs. Other). Meta-analysis provides no evidence of an association between 5-HTTLPR genotype and SSRI discontinuation for European studies (z=0.63, p=0.53) for other studies (z=0.51, p=0.61), or overall (z=0.21, p=0.8). There is evidence of an association between 5-HTTLPR genotype and SSRI discontinuation for East Asian studies (z=3.03, p=0.002). Bars represent individual study 95% confidence intervals, with a central block proportional to study size. The summary diamond bars represent the pooled effect size estimate and 95% confidence interval (CI) for the European studies, East Asian studies, other studies and all studies, as you look from top to bottom.