Fig. 4.

Static adhesion of wild-type, adhesion and degranulation-promoting adapter protein-deficient (ADAP^−/−) and Fc receptor γ-chain-deficient (FcRγ^−/−) platelets to collagen-related peptide (CRP), GFOGER, collagen, or III-04. Platelets were either untreated (control [CTRL]) or pretreated with lotrafiban (LOT: 10 μm), U46619 (U4: 2 μm), EDTA (2 mm), anti-α₂ Ha1/29 (2 μg mL⁾ ), or anti-α₁ Ha31/8 (2 μg mL⁻¹). Platelets incubated in wells coated with bovine serum albumin (BSA) or GPP showed absorbance levels equal to those of FcRγ^−/− platelets on CRP. Data labeled ‘B’ are not significantly different from responses on BSA/GPP. These data were omitted from subsequent statistical analysis. The remaining data were transformed to equalize the variance, and analyzed with anova and the Waller–Duncan post hoc test. For each peptide, homogeneous subsets are indicated. Data within the same subset are not significantly different from each other. SEM, standard error of the mean.