Table 1. Classification of carcinogenic agents according to the International Agency for Research on Cancer.
Group | Classification | Parameter | Number of agents |
---|---|---|---|
1* | Carcinogenic to humans | Sufficient evidence of carcinogenicity in humans and in experimental animals | 111 |
2A | Probably carcinogenic to humans | Limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in experimental animals | 65 |
2B | Possibly carcinogenic to humans | Limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals | 274 |
3 | The agent is not classifiable as to its carcinogenicity to humans | Inadequate evidence of carcinogenicity in humans and in experimental animals | 504 |
4 | The agent is probably not carcinogenic to humans | Evidence suggesting lack of carcinogenicity in humans and in experimental animals | 1 |
*An agent can be included in Group 1 in the absence of sufficient evidence for carcinogenicity in humans but there is sufficient data of carcinogenicity in experimental animals and strong evidence that the agent acts through a similar mechanism of carcinogenicity in humans.