Table 2. Randomized clinical trials (including more than 100 pts) of platinum-based chemotherapy plus BSC vs. BSC in advanced NSCLC.

Authors	Cytotoxic drugs	No of pts drugs/BSC	MS (mos) drugs/BSC	P value
Rapp et al./1988 (5)	CAP	198/53	5.7/3.9	0.05
Woods et al./1990 (6)	Vdp		7.5/3.9	0.01
Thongprasert et al./1999 (7)	IErP/MVdp	189/98	6.0/2.5	0.006
Cullen et al./1999 (8)	MIP	175/175	6.7/4.8	0.03
Spiro et al./2004 (9)	Cisplatin-based, MMC-Ifo-CDDP, MMC-VDS-CDDP, CDDP-VDS, CDDP-VNR	364/361	8/5.7	0.01