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. Author manuscript; available in PMC: 2014 Sep 3.
Published in final edited form as: Anal Chem. 2013 Aug 20;85(17):8046–8054. doi: 10.1021/ac401795y

Figure 8.

Figure 8

Function and interaction assays on the VirD Arrays. a. Anti-CD4 antibody staining. Strong and specific fluorescence signals were observed only on the gB:CD4 and CD4-gC virion sectors when the arrays were incubated with antibody. b. Anti-GPR77 antibody staining and GPR77-C5a ligand interaction. The antibody binds specifically to gB:GPR77 and GPR77-gC virion sectors as judged by the fluorescence signal. The Cy5-labeled C5a ligand showed strong binding activity to the GPR77-gC virion sector and weaker binding signals to the gB:GPR77 virion sector but no detectable signals on other virion sectors.