Figure 5.

Fold induction of CCR5 ligands in bronchoalveolar lavage cells after 24 h M. tuberculosis stimulation. 5 × 10⁵ BALMCs of HIV-1-infected (n = 12, open squares) and HIV-1-uninfected participants (n = 8, solid circles) were cultured for 24 h in the presence or absence of M. tuberculosis H37Rv at MOI 1:1. Fold induction was calculated as (ΔCT in the presence of H37Rv) − (ΔCT in the absence of H37Rv), values normalised by power 2^× transformation. Each symbol is representative of one sample, bars represent medians. Differences between RANTES constitutive transcript abundance of HIV-1-infected and -uninfected persons (*p = 0.034) were assessed by Mann–Whitney test. Data shown are pooled data from experiments on 12 HIV-1-infected and 8 HIV-1-uninfected persons.